Automatically Reply to Cold Emails with GPT-4 & Instantly.ai

AI-Powered Workflow for Auto-Responding to Positive Cold Email Replies

This workflow is designed for agencies, freelancers, and sales teams who want to turn positive cold email replies into booked meetings automatically—without hiring VAs or spending hours on manual responses.

❓ The Problem Most teams waste time replying manually or pay for virtual assistants, leading to delays and missed opportunities.
This template eliminates that bottleneck.

✅ What the Workflow Does Detects positive replies from Instantly.ai campaigns Uses AI to analyze intent and craft natural, human-like responses Adds personalization to keep replies authentic Includes Calendly links, product docs, or FAQs based on the lead’s intent Sends responses instantly—so you never miss a hot lead again

No robotic AI text. Just smooth, human-style emails that get booked calls faster.

👥 Who is This For? Agencies** running Instantly.ai or similar outbound tools Founders** handling their own cold email outreach Sales teams** looking to automate follow-up and booking Anyone who gets 5–20 positive replies a week and wants to 2x–4x conversions

✅ Requirements n8n** (Cloud or self-hosted) Instantly.ai account** with API access OpenAI API key** (stored securely in n8n credentials) (Optional) Calendly or booking link, Notion or Google Docs for resources

⚙️ How to Set Up Import the workflow into n8n Add your Instantly.ai API credentials and OpenAI key using n8n’s credential manager Customize the AI prompt for your tone, CTA, and offer Insert your Calendly or booking link in the response template Test with one positive reply to confirm filtering and response quality Activate the workflow to auto-reply in real time

🔧 How to Customize Adjust the filtering logic for different keywords or intent signals Add branching for multiple booking links (e.g., based on region or service type) Push responses to a CRM for tracking Include extra resources like case studies or pricing docs