Personalized B2B Cold Email Sequence with GPT-4 + Gmail Auto-Reply Detection

🎯 Automated B2B Cold Email Sequence with AI Personalization

Stop manually sending follow-ups. This workflow automates your entire cold email outreach with AI-powered personalization, smart scheduling, and automatic reply detection.

✨ What It Does

This workflow sends a perfectly-timed 3-email sequence to B2B prospects with:

AI-generated personalized emails** adapted to each prospect's sector, company size, and role Smart scheduling**: Only sends Tuesday/Wednesday/Thursday at optimal times (~9AM with randomization) Bilingual support**: Auto-detects French or English prospects Reply detection**: Automatically stops the sequence when someone replies Spam prevention**: Randomized sending times, professional intervals Full tracking**: Updates Google Sheets with send status and reply detection Slack notifications**: Get alerted immediately when a hot lead responds

📊 Expected Results

Based on real usage: 10-15% reply rate** (vs 3-8% for generic cold emails) 2-5 hot leads** per 30 prospects contacted 90% time saved** vs manual outreach Professional delivery** that preserves sender reputation

🎬 How It Works

Add prospect to Google Sheet (Email, Name, Company, etc.) Workflow triggers automatically on new row Time planning calculates optimal send dates (Tue/Wed/Thu only) Email 1 (J0): AI generates introduction with value prop (80-120 words) Wait 3 days Email 2 (J+3): Follow-up with new angle or case study (70-90 words) Wait 4 days Email 3 (J+7): Final soft close, respectful exit (60-100 words) Reply detection: Monitors Gmail → marks prospect "hot" → Slack alert → stops sequence

🚀 Perfect For

Sales teams doing B2B cold outreach Agencies prospecting new clients SaaS founders building their pipeline Consultants/freelancers doing business development Anyone tired of manual follow-ups and low response rates

⚙️ Requirements

Required: Google Sheets (free) Gmail account (free) OpenAI API key (~$0.50 per 100 emails)

Optional: Slack (for notifications)

n8n version: Compatible with n8n 1.0+

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Author:Peyrichou Maxime(View Original →)
Created:11/25/2025
Updated:11/25/2025

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